Imatinib (Piperidine)-N4-Oxide - Names and Identifiers
Imatinib (Piperidine)-N4-Oxide - Physico-chemical Properties
Molecular Formula | C29H31N7O2
|
Molar Mass | 509.6 |
Melting Point | >145°C (dec.) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Pale Yellow to Yellow |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Stability | Hygroscopic |
Imatinib (Piperidine)-N4-Oxide - Introduction
Imatinib (Piperidine)-1-oxide, also known as Imatinib N-oxide, is a chemical compound. The following is a description of the nature, use, formulation and safety information of Imatinib (Piperidine)-1-oxide:
Nature:
Imatinib (Piperidine)-1-oxide is a solid compound with a chemical formula of C29H31N7O3 and a molecular weight of 509.60. It is a white crystalline powder with good solubility and is soluble in some organic solvents such as methanol, ethanol and dimethyl sulfoxide.
Use:
Imatinib (Piperidine)-1-oxide is an important drug intermediate, which is the precursor of the tumor treatment drug Imatinib (Imatinib). Imatinib is a tyrosine kinase inhibitor that has anti-tumor activity against certain types of leukemia and other malignancies. The preparation of Imatinib (Piperidine)-1-oxide is an important step in the synthesis of Imatinib.
Preparation Method:
Imatinib (Piperidine)-1-oxide can be obtained by reacting Imatinib with hydrogen peroxide. The specific preparation method can be realized by organic synthesis chemical reaction.
Safety Information:
Imatinib (Piperidine)-1-oxide needs to be protected during use and handling, because it may be harmful to the human body. When operating, follow safe operating procedures and wear appropriate personal protective equipment, such as laboratory gloves, safety glasses and protective clothing. At the same time, it must be stored in a dry, dark, well-ventilated place, and away from fire and oxidizing agents.
Last Update:2024-04-09 21:11:58